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Research and Extracurriculars
Research and Extracurriculars
Independent Research in Biochemistry, ISEF Finalist | Alzheimer’s Drug Discovery Research
Independent Research in Biochemistry, ISEF Finalist | Alzheimer’s Drug Discovery Research
Identified Novel Target Genes and ML-based Drug Repurposing and Discovery for Alzheimer’s Disease in the Presence of Metabolic Comorbidities. Link
Oregon National Primate Research Center | Neurodegenerative Disease ASE Research Intern
Oregon National Primate Research Center | Neurodegenerative Disease ASE Research Intern
Researched interconnection of Hyaluronan, myelin, and Multiple Sclerosis and determined cognitive decline as a precursor to MS motor symptoms by implementing several wet-lab skills: Fluorescence Microscopy, qRT-PCR, Gel Electrophoresis, Immunocytochemistry, and Immunohistochemistry. Link
Rieke Neuroscience Lab, University of Washington | Neuroscience Research Intern
Rieke Neuroscience Lab, University of Washington | Neuroscience Research Intern
Distinguished primate retinal cell types using data collected on the action potential of each individual cell (ON and OFF Parasol, ON and OFF Midget).
The Global Health Leaders Conference, Johns Hopkins University | Neuroaesthetics Research
The Global Health Leaders Conference, Johns Hopkins University | Neuroaesthetics Research
Collaborated with like-minded peers learning about global health issues; presented research on Neuroaesthetics and Art Therapy for Parkinson’s Disease in a conference.
SASI, Stanford University Clinical Science, Technology and Medicine Summer Internship Program
SASI, Stanford University Clinical Science, Technology and Medicine Summer Internship Program
Trained and implemented various clinical skill techniques (gained hands-on experience with Clinical and Life-support skills such as Suturing, Intubation, CPR, Starting an IV under mentorship of attending physicians and Stanford medical students). Link
Publications
Publications
Analysis of Spinal Cord Inflammation at the Onset of Cognitive Dysfunction in a Mouse Model of Multiple Sclerosis, Shriya Pai, Kanon Yasuhara, Larry Sherman | Paper published, IJHSR
Discusses that in Multiple Sclerosis, cognitive dysfunction often occurs before the onset of significant physical disability and a definitive MS diagnosis. Despite a lack of motor symptoms in early-stage EAE mice, increased numbers of CD3 + neurons in the spinal cord illustrate the role of inflammation in MS wherein hippocampal learning and memory are first affected.
Identification of Novel Target Genes for Alzheimer’s Disease in the Presence of Metabolic Comorbidities, Shriya Pai | Paper Accepted and under final copy edit review, JEI
Provides an overview of comparison of AD and comorbidities; differential gene expressions, to find common genes, like AKT1, CHUK, PPM1A, and STARD3NL that correlated directly to the AD pathway through literature studies and STRING/GO pathway analyses.
Awards and Honors
Awards and Honors
Regeneron ISEF (Intl. Science & Engineering Fair) Finalist, NorthWest Science Expo, 1st Place | Science Fair______________________2024
President’s Volunteer Service Award (PVSA), Silver | Volunteering______________________________________________________________ 2023-24
USNCO | National Chemistry Olympiad Nationalist__________________________________________________________________________2023, 2024
USABO | USA Biology Olympiad Semifinalist________________________________________________________________________________________2024
Broadcom MASTERS Nominee | Science Fair________________________________________________________________________________________2021
Skills
Skills
Excellent communication skills and team player.
Creative thinking, leadership and problem-solving skills
Java, Python, MATLAB (Inter), R (Inter), ImageJ
Wet lab skills (cell culture, PCR, blotting Immunohistochemistry, Fluorescence imaging)
Volunteering
Volunteering
Volunteer, OHSU Hospital & Doernbecher Children’s Hospital | 4 hrs/week _________________________________________ Jun 2023 - present
~200 hours of service at the hospital guiding and assisting patients and families
Volunteer, Memory care/Assisted Living | 4 hrs/week __________________________________________________________________ Jun 2024 - present
~80 hours of service assisting elderly with tasks and art therapy
Mentor, ONPRC Science Ambassador program| 2 hrs/week __________________________________________________________ Oct 2023 - May 2023 & Oct 2024 - current
~50x2 hour program - Develop lessons and hands-on activities to mentor 5th graders from local school district on STEM as part of Oregon National Primate Research Center
Tutor, ‘Learn To Be’ Online Learning Platform | ~1 hr/week ___________________________________________________________ Aug 2023 - present
~20 hours of tutoring underserved students in math and reading.
Volunteer Meal Server, Blanchet House | 2 hrs/month_________________________________________________________________ June 2021- present
~40 hours of serving hot meals for the underprivileged and houseless community. Links to my Labor day meal service https://www.kptv.com/2023/09/05/blanchet-house-serves-hundreds-labor-day/
Leadership
Leadership
Leader, Research & Science Fair Club, Jesuit High School | 2 hrs/week August 2024 - present
As the club leader, organize meetings, guide students to perform research and participate in science fair.
Founder, Project Art on Wheels | 4 hrs/month Jun 2024 - present
Art therapy for neurorehabilitation with the goal to bring art (visual, hands-on) to assisted living and memory care centers around the world.
Founder, STEMtopia, Advanced STEM tutoring for Title I schools, Portland, OR | 2 hrs/week Sept 2024 - present
Advanced learning and tutoring for students in Portland Public school district with the goal to provide STEM access to all (including introduction of competitive Biology, Chemistry and Math).
Talks and Symposiums
Talks and Symposiums
Invited speaker at Oregon Health Care Association, Fall 2024
Invited speaker at Oregon Health Care Association, Fall 2024
The Art of Innovation, Oregon Health Care Association (OHCA) | Oregon Convention Center, Portland, OR
The Art of Innovation, Oregon Health Care Association (OHCA) | Oregon Convention Center, Portland, OR
Invited to present on the benefits of Art Therapy for neurorehabilitation to enable implementation of art activities at memory care centers to measurably improve the quality of life and emotional well-being of people with dementia, cognitive dysfunction.
Invited to present on the benefits of Art Therapy for neurorehabilitation to enable implementation of art activities at memory care centers to measurably improve the quality of life and emotional well-being of people with dementia, cognitive dysfunction.
Summer Internship, sophomore year (2024)
Summer Internship, sophomore year (2024)
Apprenticeship in Science and Engineering (ASE) Symposium | OHSU ONPRC, Beaverton, OR
Apprenticeship in Science and Engineering (ASE) Symposium | OHSU ONPRC, Beaverton, OR
Research internship presentation on Degree of Spinal Cord Inflammation at the Onset of Cognitive Dysfunction in a Mouse Model of Multiple Sclerosis showing how increased numbers of CD3+ lymphocytes in the spinal cord illustrate the role of inflammation in MS when hippocampal learning and memory are first affected.
Research internship presentation on Degree of Spinal Cord Inflammation at the Onset of Cognitive Dysfunction in a Mouse Model of Multiple Sclerosis showing how increased numbers of CD3+ lymphocytes in the spinal cord illustrate the role of inflammation in MS when hippocampal learning and memory are first affected.
Summer Internship, junior year (2025)
Summer Internship, junior year (2025)
Clark Scholar presentation 2025-08-06 Shriya.mp4Clark Scholars Research program | Texas Tech University, TX
Clark Scholars Research program | Texas Tech University, TX
Research internship presentation on how loss of DNase1L3 gene promotes systemic inflammation and suggests a role in neuroinflammatory process in Lupus Mouse model.
Research internship presentation on how loss of DNase1L3 gene promotes systemic inflammation and suggests a role in neuroinflammatory process in Lupus Mouse model.
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